A Negative (A−) Blood Group
A− is group A with RhD-negative status. For red-cell transfusion, group A patients can receive A or O red cells, while RhD-negative patients are generally matched with RhD-negative red cells.
Medical information notice: This article explains general blood-group concepts. Actual transfusion decisions are made by qualified clinical and transfusion-service staff after appropriate testing.
What does A Negative (A−) mean?
A− is group A with RhD-negative status. For red-cell transfusion, group A patients can receive A or O red cells, while RhD-negative patients are generally matched with RhD-negative red cells.
Red-cell compatibility
A− red cells can be used for A− and AB− recipients under standard ABO/Rh red-cell compatibility. Blood services perform compatibility testing before transfusion.
Why compatibility testing still matters
RhD status matters because RhD-negative recipients can develop anti-D antibodies after exposure to RhD-positive red cells. This is one reason transfusion services consider RhD compatibility carefully.
Sources
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